Good transfer of passive immunity from sows to piglets is crucial to ensure piglet survival on pig farms. This book is intended to help veterinary practitioners work towards this goal, and includes a review of the basics of immunology and vaccination, as well as comprehensive chapters on the immunization programs used in sows and on the transfer of passive immunity from sows to piglets.
KEY FEATURES:
➜ Visual and practical approach.
➜ Designed to be used as a reference tool for the reader.
➜ Includes a review of the basics of immunology and vaccination.
Author:
Lorenzo José Fraile Sauce
Degree in Veterinary Medicine (1992) and Doctor of Veterinary Pharmacology in 1996, both from the University of Zaragoza, Spain, then specialist pig vet for Cargill España S.A. and Picber S.A. until 2004. Researcher at the Centre de Recerca en Sanitat Animal (CReSA; Centre for Animal Health Research) from 2004 to 2010, where he was head of the Department of Epidemiology, Disease Control and Clinical Trials. Collaborator with the European Medicines Agency from 2005 to 2007, assessing veterinary medicines submitted for registration in Europe through his work on the Committee for Medicinal Products for Veterinary Use (CVMP). Member of the Scientific Advice Group on Antimicrobials, which provides scientific advice on all aspects of the use of antimicrobials in veterinary medicine to CVMP, from 2006 to 2007. Adjunct professor of Epidemiology and Pharmacology at the University of Lleida since 2010, and involved in teaching the Masters Degree in Swine Production and Health offered by the Complutense University of Madrid, the University of Lleida and the University of Zaragoza. His current fields of scientific interest are epidemiology, immunology and clinical pharmacology, and his research aims to optimize preventative medicine programs in pigs. He is the author of over 80 articles published in international scientific journals and 130 papers presented at national and international conferences. Finally, he has been a speaker at many veterinary conventions.
Table of contents:
1. Introduction
Basic immunological concepts
Innate immunity
Cellular component
Humoral component
Adaptive (acquired) immunity
Humoral component
Cellular component
Dynamics of the immune response
Relative importance of cellular and humoral immunity in effective protection
2. General principles of vaccines and vaccination
Introduction
Methods of active artificial immunisation
Practical vaccine application
Adverse reactions to vaccines
3. Transfer of passive immunity to the piglet
Passive immunity and its role in the piglet
Introduction
Colostrum, transient milk and mature milk
The role of colostrum in newborn piglet survival
Transfer of humoral and cellular immunity
Introduction
Humoral immunity
Cellular immunity
Strategy for improving the transfer of passive immunity
Interference with active immunity by passive immunity
Introduction
Interference with the development of humoral immunity
Interference with the development of cellular immunity
Strategies to overcome maternal immunity and develop effective active immunity in the newborn
4. Prevention programmes in pigs
Basic concepts
Bacterial diseases: sow vaccination programmes
Vaccination against exotoxin–producing bacteria
Vaccination against extracellular bacteria
Viral diseases: sow vaccination programmes
Vaccination against porcine reproductive and respiratory syndrome
Vaccination against porcine circovirus disease
Vaccination against parvovirus infection
Vaccination against swine influenza
5. Practical aspects of the transfer of passive immunity to the piglet
Management of colostrum consumption1
Factors related to quality
Factors related to quantity
Measuring the transfer of passive immunity
References
